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Publications


Insights on Future Directions in Cancer Research from the 2026 AACR NextGen Stars


CheukMan Cherie Au, Daniel D. Azorín, Jian Carrot-Zhang, Steven M. Corsello, Alvaro Curiel-Garcia, William Freed-Pastor, Adam J. Grippin, Long Chi Nguyen, Ray Pillai, Amulya Sreekumar, Daniel J. Zabransky

Cancer Discovery, vol. 16, American Association for Cancer Research (AACR), 2026 Apr, pp. 670–676


Residual Breast Cancer Cells Co-opt SOX5-Driven Endochondral Ossification to Maintain Dormancy


Amulya Sreekumar, Eric Blankemeyer, Christopher J. Sterner, Tien-Chi Pan, Dhruv K. Pant, Sarah Acolatse, Hamza Turkistani, George K. Belka, Anupma Nayak, Sean D. Carlin, Charles-Antoine Assenmacher, Mark A. Sellmyer, David A. Mankoff, Lewis A. Chodosh

Cancer Discovery, vol. 16, American Association for Cancer Research (AACR), 2025 Dec, pp. 781–799


Residual Breast Cancer Cells Co-opt SOX5-driven Endochondral Ossification to Maintain Dormancy


Amulya Sreekumar, Eric Blankemeyer, Christopher J. Sterner, Tien-Chi Pan, Dhruv K. Pant, Sarah Acolatse, Hamza Turkistani, George K. Belka, Sean D. Carlin, Charles A. Assenmacher, Mark A. Sellmyer, David A. Mankoff, Lewis A. Chodosh

bioRxiv, openRxiv, 2025 May


B3GALT6 promotes dormant breast cancer cell survival and recurrence by enabling heparan sulfate-mediated FGF signaling


Amulya Sreekumar, Michelle Lu, Biswa Choudhury, Tien-chi Pan, Dhruv K. Pant, Matthew R. Lawrence-Paul, Christopher J. Sterner, George K. Belka, Takashi Toriumi, Brian A. Benz, Matias Escobar-Aguirre, Francesco E. Marino, Jeffrey D. Esko, Lewis A. Chodosh

Cancer Cell, vol. 42, Elsevier BV, 2024 Jan, pp. 52–69.e7


Dormancy in Breast Cancer


Erica Dalla, Amulya Sreekumar, Julio A. Aguirre-Ghiso, Lewis A. Chodosh

Cold Spring Harbor Perspectives in Medicine, vol. 13, Cold Spring Harbor Laboratory, 2023 Apr, pp. a041331


B3GALT6 Promotes Dormant Breast Cancer Cell Survival and Recurrence by Enabling Heparan Sulfate-Mediated FGF Signaling


Amulya Sreekumar, Michelle Lu, Biswa Choudhury, Tien-chi Pan, Dhruv K. Pant, Christopher J. Sterner, George K. Belka, Takashi Toriumi, Brian Benz, Matias Escobar-Aguirre, Francesco E. Marino, Jeffrey D. Esko, Lewis A. Chodosh

bioRxiv, openRxiv, 2023 Feb


PAQR8 promotes breast cancer recurrence and confers resistance to multiple therapies


Saisai Chen, Matt R. Paul, Christopher J. Sterner, George K. Belka, Dezhen Wang, Peining Xu, Amulya Sreekumar, Tien-chi Pan, Dhruv K. Pant, Igor Makhlin, Angela DeMichele, Clementina Mesaros, Lewis A. Chodosh

Breast Cancer Research, vol. 25, Springer Science and Business Media LLC, 2023 Jan


WNT-Mediated Regulation of FOXO1 Constitutes a Critical Axis Maintaining Pubertal Mammary Stem Cell Homeostasis


Amulya Sreekumar, Michael J. Toneff, Eajer Toh, Kevin Roarty, Chad J. Creighton, George K. Belka, Dong-Kee Lee, Jianming Xu, Lewis A. Chodosh, JoAnne S. Richards, Jeffrey M. Rosen

Developmental Cell, vol. 43, Elsevier BV, 2017 Nov, pp. 436–448.e6


The Z-cad dual fluorescent sensor detects dynamic changes between the epithelial and mesenchymal cellular states


M. J. Toneff, A. Sreekumar, A. Tinnirello, P. Den Hollander, S. Habib, S. Li, M. J. Ellis, L. Xin, S. A. Mani, J. M. Rosen

BMC Biology, vol. 14, Springer Science and Business Media LLC, 2016 Jun


A Geometrically-Constrained Mathematical Model of Mammary Gland Ductal Elongation Reveals Novel Cellular Dynamics within the Terminal End Bud


Ingrid Paine, Arnaud Chauviere, John Landua, Amulya Sreekumar, Vittorio Cristini, Jeffrey Rosen, Michael T. Lewis

Alexandre V Morozov, PLOS Computational Biology, vol. 12, Public Library of Science (PLoS), 2016 Apr, pp. e1004839


The mammary stem cell hierarchy: a looking glass into heterogeneous breast cancer landscapes


Amulya Sreekumar, Kevin Roarty, Jeffrey M Rosen

Endocrine-Related Cancer, vol. 22, Bioscientifica, 2015 Jul, pp. T161–T176


Transgenic expression of oncogenic BRAF induces loss of stem cells in the mouse intestine, which is antagonized by β-catenin activity


P Riemer, A Sreekumar, S Reinke, R Rad, R Schäfer, C Sers, H Bläker, B G Herrmann, M Morkel

Oncogene, vol. 34, Springer Science and Business Media LLC, 2014 Aug, pp. 3164–3175


Wnt and BMP signals control intestinal adenoma cell fates


Alexandra L. Farrall, Pamela Riemer, Marc Leushacke, Amulya Sreekumar, Christina Grimm, Bernhard G. Herrmann, Markus Morkel

International Journal of Cancer, vol. 131, Wiley, 2012 Mar, pp. 2242–2252

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